Octreotide

• Octreotide is another medication option that has been used for individuals who have not responded to other medication options.

• When assessing its effectiveness for these individuals, all of whom had POTS, symptom reduction (though variable) was seen; more specifically, researchers found a reduction in orthostatic intolerance, syncope, standing heart rate, and an increase in systolic blood pressure (Kanjwal et al., 2012).

Source:

Kanjwal, K., Saeed, B., Karabin, B., Kanjwal, Y., & Grubb, B. P. (2012). Use of octreotide in the treatment of refractory orthostatic intolerance. American Journal of Therapeutics, 19(1), 7–10. https://doi.org/10.1097/mjt.0b013e3181e28156